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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R8
All Species:
30.3
Human Site:
Y264
Identified Species:
55.56
UniProt:
Q12972
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12972
NP_002704.1
351
38479
Y264
F
A
F
S
G
G
L
Y
G
G
L
P
P
T
H
Chimpanzee
Pan troglodytes
XP_001150604
378
41336
Y264
F
A
F
S
G
G
L
Y
G
G
L
P
P
T
H
Rhesus Macaque
Macaca mulatta
XP_001112289
378
41328
Y264
F
A
F
S
G
G
L
Y
G
G
L
P
P
T
H
Dog
Lupus familis
XP_865789
355
39236
Y268
F
A
F
S
G
G
L
Y
G
G
L
P
P
T
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3G1
351
38509
Y264
F
A
F
S
G
G
L
Y
G
G
L
P
P
T
H
Rat
Rattus norvegicus
NP_001101381
351
38521
Y264
F
A
F
S
G
G
L
Y
G
G
L
P
P
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518825
234
26189
D148
E
K
M
G
G
E
D
D
E
L
K
G
L
L
G
Chicken
Gallus gallus
NP_001026062
354
38600
Y265
F
P
Y
S
G
G
L
Y
G
G
L
P
P
T
H
Frog
Xenopus laevis
NP_001083528
346
37932
G259
Q
N
F
P
F
T
G
G
L
Y
G
G
L
P
P
Zebra Danio
Brachydanio rerio
NP_001094422
351
38384
Y261
F
P
L
S
G
G
L
Y
G
D
L
P
P
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611177
383
42555
F255
A
A
H
V
H
Q
M
F
Q
Q
S
L
V
D
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492781
302
33933
G216
T
N
P
N
K
R
P
G
D
P
K
R
S
E
P
Sea Urchin
Strong. purpuratus
XP_001199058
347
38163
D259
N
Y
G
P
N
L
Y
D
N
L
P
L
S
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.8
91.2
89
N.A.
98
97.7
N.A.
65.8
88.6
82.9
77.7
N.A.
47.5
N.A.
39
51.5
Protein Similarity:
100
91.8
91.5
90.4
N.A.
98.5
98.5
N.A.
66
93.2
89.7
88
N.A.
62.1
N.A.
53.8
67.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
86.6
6.6
73.3
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
93.3
6.6
73.3
N.A.
20
N.A.
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
16
8
8
0
0
0
8
0
% D
% Glu:
8
0
0
0
0
8
0
0
8
0
0
0
0
8
0
% E
% Phe:
62
0
54
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
70
62
8
16
62
54
8
16
0
0
16
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
54
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
8
0
0
0
0
0
16
0
0
0
0
% K
% Leu:
0
0
8
0
0
8
62
0
8
16
62
16
16
8
0
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
8
16
0
8
8
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
16
8
16
0
0
8
0
0
8
8
62
62
8
16
% P
% Gln:
8
0
0
0
0
8
0
0
8
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
62
0
0
0
0
0
0
8
0
16
8
8
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
0
0
0
62
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
8
62
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _